Prognostischer Wert perioperativ beim Empfanger bestimmter Parameter fur den Erfolg der Nierentransplantation

Translated title of the contribution: Effect of recipients' perioperative parameters to the outcome of kidney transplantation

M. Tóth, V. Réti, T. Gondos

Research output: Contribution to journalArticle

Abstract

Objective: to examine how to influence the preoperative recipient parameters of the transplanted kidney function in every day practice. Design: retrospective, multifactorial analysis. Patients: 104 patients who underwent first cadaver kidney transplantation in our unit between January and December in 1992 were involved in the study and were followed up for another 2 years. The recipients were devided into 3 groups: Group I: non functioning graft (n = 13); Group II: delayed graft function (n = 49); Group III: good graft function (n = 42). The grouping criteria were: a) haemodialysis in the first 5 postoperative days, b) quantity of diuresis on the first postoperative day, c) serum creatinine difference between the first postoperative day compared to the preoperative level. All of the parameters that we measure in our every day practice were involved in the examination. Results: The preoperative hematocrit level differed significantly between Group III (0.30) and Group I and Group II (0.35 and 0.32 respectively, p < 0.05). Intraoperative significant differences were found between the different groups in systolic blood pressure, mean arterial pressure pulse-amplitude and in rate pressure product. The patients who had better postoperative kidney function had higher blood pressure in the different phase of operation than the patients who had postoperative kidney function problems. The second warm ischaemic time in Group III was significantly shorter than in the other two groups (Group III 37 min. vs. Group II 42 min. p < 0.05, vs. Group I 48 min. P < 0.001). The rejection rate was higher during the first 5 postoperative days in patients with non-functioning grafts (Group I 53% and Group II 24% vs. Group III 12%). The other examined parameters have not differed significantly. The observed kidney function differences in the early postoperative period between the 3 groups remained until the end of the next 2 years. Conclusions: According to our results the perioperative fluid-balance is one of the most important factors which may influence the success of the kidney transplantation.

Original languageGerman
Pages (from-to)75-80
Number of pages6
JournalNieren- und Hochdruckkrankheiten
Volume26
Issue number2
Publication statusPublished - Feb 1 1997

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Keywords

  • blood pressure-heart rate product
  • delayed renal function
  • fluid balance
  • hematocrit
  • non functioning renal transplant
  • primary renal function
  • pulse amplitude
  • renal graft function
  • renal transplantation

ASJC Scopus subject areas

  • Internal Medicine
  • Nephrology

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