Effect of prolonged heavy exercise on passive biomechanics of splanchnic and cranial blood vessels in dogs

L. A. Szirmai, V. Bérczi, M. Szentiványi, E. Marin, O. Hänninen, E. Monos

Research output: Contribution to journalArticle

Abstract

Biomechanical changes of large arteries and veins of the splanchnic and cranial regions were studied in dogs subjected to heavy treadmill exercise during a 55 week period. Passive stress-strain properties of the vessels were determined using an in-vitro large-deformation mechanical test. External, internal radii, and consequently lumen capacity per unit length of splenic veins were significantly larger in trained versus sedentary dogs at each intraluminal pressure (IP) level studied (e.g. lumen volume at IP of 8 mmHg: 0.276 ± 0.044 cm3/cm vs. 0.132 ± 0.027 cm3/cm; p < 0.05). Similar results were obtained from renal veins (0.155 ± 0.019 cm3/cm vs. 0.068 ± 0.027 cm3/cm, at 8 mmHg; p < 0.05). However, wall thicknesses of visceral veins from trained and sedentary dogs were nearly identical. No differences in geometrical properties of the internal jugular vein and all the arteries (splenic, renal, common carotid) were found between the two groups. Similarly, elastic parameters (distensibility, elastic modulus, wall stresses, characteristic impedance, etc.) of vessels from all regions proved to be identical in the two groups. In conclusion, increased passive caliber present only in visceral veins may reflect a regionally specific capacity adaptation to exercise-induced hypervolemia.

Original languageEnglish
Pages (from-to)15-24
Number of pages10
JournalPathophysiology
Volume4
Issue number1
DOIs
Publication statusPublished - Mar 1 1997

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Keywords

  • arteries
  • exercise
  • vascular biomechanics
  • vascular elasticity
  • veins
  • venous capacity

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Physiology (medical)

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