Effect of phencyclidine (PCP) on blood pressure and catecholamine levels in discrete brain nuclei

Mohamed A. Bayorh, Zofia Zukowska-Grojec, Miklos Palkovits, Irwin J. Kopin

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

PCP (10mg/kg, s.c.) causes hypertension that is associated with decrease or tendency to decrease the levels of epinephrine and norpinephrine in the hypothalamus and the brainstem regions. If this represents a decreased catecholaminergic activity, then this may enhance sympathetic activity and contribute to the PCP-induced hypertension.

Original languageEnglish
Pages (from-to)315-318
Number of pages4
JournalBrain research
Volume321
Issue number2
DOIs
Publication statusPublished - Nov 12 1984

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Keywords

  • PCP
  • brainstem
  • catecholamines
  • hypertension
  • hypothalamic

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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