Effect of oxytocin and its analogues on the chemotaxis of Tetrahymena

Evolutionary conclusions

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Oxytocin and its five analogues (arginin vasopressin included) were studied in chemotaxis assays using Tetrahymena as unicellular model cells. Exclusively the two real hormones (oxytocin and vasopressin) were consequently repellent, other analogues (with exchanged or missed amino acids) were neutral, attractant or unbalanced. Tetrahymena was not able to differentiate qualitatively between oxytocin and vasopressin, however it sharply discriminated the real hormones from the analogues. Considering that in earlier experiments oxytocin and vasopressin also equally influenced the function of the contractile vacuole, it is supposed that the uniformity of the effect of these hormones is not a chance event and they had to be diverged (in function) later, during the evolution.

Original languageEnglish
Pages (from-to)345-347
Number of pages3
JournalActa Protozoologica
Volume39
Issue number4
Publication statusPublished - 2000

Fingerprint

Tetrahymena
vasopressin
oxytocin
chemotaxis
Chemotaxis
Oxytocin
Vasopressins
hormones
Hormones
Neutral Amino Acids
attractants
repellents
Vacuoles
vacuoles
amino acids
assays
cells

Keywords

  • Chemotaxis
  • Evolution
  • Neurohypophyseal hormones
  • Tetrahymena

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Agricultural and Biological Sciences (miscellaneous)
  • Microbiology

Cite this

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AU - Kovács, K.

AU - Kőhidai, L.

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