Effect of neomycin on glycosyl-phosphatidylinositol and phosphatidylinositol system of Tetrahymena

P. Kovács, G. Csaba

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Neomycin does not inhibit but increases the incorporation of 32P into phosphatidylinositols of Tetrahymena. This elevation is due to neomycin inhibition on the turnover of the phosphatidylinositol (PI) system. Neomycin also prevents the synthesis of glycosyl-phosphatidylinositol (GPI). These experiments draw attention to the inhibitory effect of neomycin both on GPI synthesis and Pl turnover, and the connection between these systems. An explanation for the inhibitory effect of neomycin on hormonal imprinting is discussed.

Original languageEnglish
Pages (from-to)7-18
Number of pages12
JournalMicrobios
Volume84
Issue number342
Publication statusPublished - 1996

Fingerprint

Tetrahymena
Glycosylphosphatidylinositols
Neomycin
Phosphatidylinositols

Keywords

  • Hormonal imprinting
  • Neomycin
  • Phosphatidylinositols
  • Tetrahymena

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Effect of neomycin on glycosyl-phosphatidylinositol and phosphatidylinositol system of Tetrahymena. / Kovács, P.; Csaba, G.

In: Microbios, Vol. 84, No. 342, 1996, p. 7-18.

Research output: Contribution to journalArticle

@article{1cd96bb7e0a4490c880ca45fa0c19dcf,
title = "Effect of neomycin on glycosyl-phosphatidylinositol and phosphatidylinositol system of Tetrahymena",
abstract = "Neomycin does not inhibit but increases the incorporation of 32P into phosphatidylinositols of Tetrahymena. This elevation is due to neomycin inhibition on the turnover of the phosphatidylinositol (PI) system. Neomycin also prevents the synthesis of glycosyl-phosphatidylinositol (GPI). These experiments draw attention to the inhibitory effect of neomycin both on GPI synthesis and Pl turnover, and the connection between these systems. An explanation for the inhibitory effect of neomycin on hormonal imprinting is discussed.",
keywords = "Hormonal imprinting, Neomycin, Phosphatidylinositols, Tetrahymena",
author = "P. Kov{\'a}cs and G. Csaba",
year = "1996",
language = "English",
volume = "84",
pages = "7--18",
journal = "Microbios",
issn = "0026-2633",
publisher = "University of Cambridge",
number = "342",

}

TY - JOUR

T1 - Effect of neomycin on glycosyl-phosphatidylinositol and phosphatidylinositol system of Tetrahymena

AU - Kovács, P.

AU - Csaba, G.

PY - 1996

Y1 - 1996

N2 - Neomycin does not inhibit but increases the incorporation of 32P into phosphatidylinositols of Tetrahymena. This elevation is due to neomycin inhibition on the turnover of the phosphatidylinositol (PI) system. Neomycin also prevents the synthesis of glycosyl-phosphatidylinositol (GPI). These experiments draw attention to the inhibitory effect of neomycin both on GPI synthesis and Pl turnover, and the connection between these systems. An explanation for the inhibitory effect of neomycin on hormonal imprinting is discussed.

AB - Neomycin does not inhibit but increases the incorporation of 32P into phosphatidylinositols of Tetrahymena. This elevation is due to neomycin inhibition on the turnover of the phosphatidylinositol (PI) system. Neomycin also prevents the synthesis of glycosyl-phosphatidylinositol (GPI). These experiments draw attention to the inhibitory effect of neomycin both on GPI synthesis and Pl turnover, and the connection between these systems. An explanation for the inhibitory effect of neomycin on hormonal imprinting is discussed.

KW - Hormonal imprinting

KW - Neomycin

KW - Phosphatidylinositols

KW - Tetrahymena

UR - http://www.scopus.com/inward/record.url?scp=0029682381&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029682381&partnerID=8YFLogxK

M3 - Article

VL - 84

SP - 7

EP - 18

JO - Microbios

JF - Microbios

SN - 0026-2633

IS - 342

ER -