Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: The nuheal trial

Tamás Decsi, Cristina Campoy, Berthold Koletzko

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

In this placebo controlled, randomised, double blind trial, pregnant women received from the 20th week of gestation onwards either 500 mg docosahexaenoic acid (DHA), 400 mg 5-methyl-tetra-hydro-folate (5-MTHF), or placebo, or a combination of 500 mg DHA and 400 mg 5-MTHF. The dietary supplements were well tolerated; the dropout rates did not differ significantly in the active arms of the study (10% to 19%) from that seen in the placebo group (13%). DHA supplementation resulted in significant enhancement of the contribution of DHA to maternal, placental and venous cord blood lipids.

Original languageEnglish
Pages (from-to)109-113
Number of pages5
JournalAdvances in experimental medicine and biology
Volume569
DOIs
Publication statusPublished - Dec 1 2005

Keywords

  • Docosahexaenoic acid
  • Fetal nutrition
  • Long-chain polyunsaturated fatty acid
  • Methyl-tetra-hydro-folate
  • Pregnancy

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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