Effect of Mytilus inhibitory peptide on identified molluscan neurons

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1. 1. MIP isolated from Mytilus ganglia hyperpolarizes neurons of Helix pomatia L. inducing voltage independent small outward current. 2. 2. The neuropeptide modulates the membrane Ca-conductance, in most of the cells investigated, decreasing the ICa and Ca-activated potassium currents. 3. 3. MIP increases the delayed outward currents and decreases the Ca-dependent K-current. 4. 4. The Mytilus inhibitory neuropeptide exerted a combination of more than one type of action on the Helix neurons, and in this respect its effect resembled other molluscan neuropeptides.

Original languageEnglish
Pages (from-to)207-212
Number of pages6
JournalComparative Biochemistry and Physiology. Part C, Comparative
Issue number2
Publication statusPublished - 1990


ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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