Effect of ionic milieu to the free radicals generated by phenizine methosulphate (PMS).

T. Past, I. Wittmann, J. Belágyi, T. Jávor

Research output: Contribution to journalArticle

Abstract

The effect of free radicals generated by PMS was studied for membrane damage in the presence of different ions in the erythrocyte model. The degree of membrane damage depended on the quality of ionic composition in the incubation medium. We supposed that the degree of membrane damage depends on the average life and concentration and/or reactivity of the free radicals generated. For control of this supposition free radicals were generated by PMS in the presence of Sodium-di-thionite in isosmotic, waterly systems with different ionic composition. At different time intervals the concentration of free radicals was measured by the ESR method. It seams that concentration of radicals depends on the qualitative composition of ionic milieu. The increase of the average life of free radicals generated by PMS is accompanied by decrease in their reactivity. This is reflected by a moderate membrane damage.

Original languageEnglish
Pages (from-to)347-349
Number of pages3
JournalActa Physiologica Hungarica
Volume73
Issue number2-3
Publication statusPublished - 1989

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Free Radicals
Membranes
Erythrocytes
Sodium
Ions

ASJC Scopus subject areas

  • Physiology

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Effect of ionic milieu to the free radicals generated by phenizine methosulphate (PMS). / Past, T.; Wittmann, I.; Belágyi, J.; Jávor, T.

In: Acta Physiologica Hungarica, Vol. 73, No. 2-3, 1989, p. 347-349.

Research output: Contribution to journalArticle

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