Effect of ion pairing on the fluorescence of berberine, a natural isoquinoline alkaloid

Mónika Megyesi, László Biczók

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Effect of association with chloride or perchlorate anions on the fluorescence properties of berberine, a cationic isoquinoline alkaloid, has been studied. Interaction with Cl- caused more efficient fluorescence quenching; it significantly accelerated the radiationless deactivation and slowed down the radiative transition. Combined analysis of spectrophotometric, steady-state and time-resolved fluorescence results provided 1.5 × 105 M-1 for the equilibrium constant of ion pairing with Cl- in CH2Cl2. Both ion pairing and enrichment of the microenvironment of berberine in ions led to excited state quenching in solvents of medium polarity, but only the latter effect was observed in the presence of perchlorates in butyronitrile.

Original languageEnglish
Pages (from-to)247-251
Number of pages5
JournalChemical Physics Letters
Volume447
Issue number4-6
DOIs
Publication statusPublished - Oct 25 2007

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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