Effect of immunosuppressive therapy on the serum glycoprotein levels in chronic aggressive hepatitis

J. Fehér, L. Jakab, I. Sule, J. Tenczer, I. Szilvási, G. Papp

Research output: Contribution to journalArticle

Abstract

The sera of 24 patients with chronic aggressive hepatitis receiving combined immunosuppressive therapy were studied for the concentrations of the carbohydrate components of glycoproteins and the IgG, IgA, IgM, alpha-2-macroglobulin, coeruloplasmin, beta-1-C-globulin and transferrin levels over a period of 2 years. Liver biopsy was performed repeatedly in 50% of the cases. On the evidence of the results, combined immuno suppressive treatment is regarded as apt to normalize the serum concentrations of IgG, IgA, IgM and to reduce those of alpha-2-macroglobulin and coeruloplasmin. Among the carbohydrate components of glycoproteins only the amount of hexose was reduced.

Original languageEnglish
Pages (from-to)207-215
Number of pages9
JournalActa Medica Academiae Scientiarum Hungaricae
Volume33
Issue number3
Publication statusPublished - 1976

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ASJC Scopus subject areas

  • Medicine(all)

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