Effect of immunosuppressive therapy on lymphocyte populations in patients with chronic active hepatitis

J. Fehér, T. Pozsonyi, L. Jakab, G. Filipp

Research output: Contribution to journalArticle

Abstract

The number of circulating lymphocytes and the number of B and T lymphocytes were estimated in blood samples of 38 patients with biopsy-verified chronic active hepatitis before and after combined immunosuppressive therapy. In chronic active hepatitis, the numnber of total lymphocytes and T cells decreased; the B lymphocytes showed no evaluable change. Immunosuppressive therapy led to a further decrease of total lymphocytes and of T and B cells. The decrease of IgG- and IgM-bearing lymphocytes was parallel to the reduction of corresponding immunoglobulin concentration. These data indicate that immunosuppressive therapy with steroids and azathioprine further affects the immune reaction in chronic active hepatitis.

Original languageEnglish
Pages (from-to)39-47
Number of pages9
JournalActa Medica Academiae Scientiarum Hungaricae
Volume38
Issue number1
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Effect of immunosuppressive therapy on lymphocyte populations in patients with chronic active hepatitis'. Together they form a unique fingerprint.

  • Cite this