Effect of hyperventilation on cerebral blood flow velocity in preeclamptic pregnancies: Is there evidence for an altered cerebral vasoreactivity?

J. Zatik, J. Aranyosi, C. Molnár, D. Páll, A. Borsos, B. Fülesdi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The purpose of this study was to investigate cerebral arteriolar vasoreactivity function in preeclampsia. Preeclamptic (n = 26) and healthy pregnant (n = 22) women underwent transcranial Doppler sonography of the middle cerebral artery at rest and after 60 seconds of hyperventilation (HV). Systolic, diastolic, and mean blood flow velocities were recorded. The percentage change of the blood flow velocities after HV was calculated. Mean blood flow velocity of the middle cerebral artery was higher in preeclamptic women as compared with healthy pregnant women. No difference could be detected in percentage change of middle cerebral artery blood flow velocities after HV between the two groups. There is no evidence of a small-vessel vasoconstriction among preeclamptic patients. The role of vasoconstriction of the large cerebral arteries and vasodilation of the resistance arterioles, as well as a combination of these 2 pathomechanisms, in determining cerebral blood flow in preeclampsia and eclampsia should be investigated in further studies.

Original languageEnglish
Pages (from-to)179-183
Number of pages5
JournalJournal of Neuroimaging
Volume11
Issue number2
Publication statusPublished - 2001

Fingerprint

Cerebrovascular Circulation
Hyperventilation
Blood Flow Velocity
Middle Cerebral Artery
Pregnancy
Pre-Eclampsia
Vasoconstriction
Doppler Transcranial Ultrasonography
Eclampsia
Cerebral Arteries
Arterioles
Vasodilation
Pregnant Women

Keywords

  • Cerebral vasoreactivity
  • Hyperventilation
  • Preeclampsia
  • Transcranial Doppler sonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Neuroscience(all)
  • Radiological and Ultrasound Technology

Cite this

Effect of hyperventilation on cerebral blood flow velocity in preeclamptic pregnancies : Is there evidence for an altered cerebral vasoreactivity? / Zatik, J.; Aranyosi, J.; Molnár, C.; Páll, D.; Borsos, A.; Fülesdi, B.

In: Journal of Neuroimaging, Vol. 11, No. 2, 2001, p. 179-183.

Research output: Contribution to journalArticle

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