Effect of F- on major salivary glands. The amylase activity, stimulated salivary flow response and cAMP levels in parotid gland of rats consuming F- via drinking water

I. Boros, G. Mózsik, P. Keszler

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Abstract

This study examined the effect of intakes of 25 or 50 ppm fluoride via drinking water for four weeks on the amylase activity of the parotid gland, isoproterenol-stimulated (1 mg/100 g b.w., i.p.) salivary flow and on the amylase activity in saliva fractions. A significant elevation of the tissue amylase activity was seen in the F25 and F50 groups compared to control The volume of saliva collected for 30 min after isoproterenol injection was higher in the fluoride-treated groups; the amylase activity was also increased. In the glandular tissue cAMP level was augmented. It appears that fluoride may affect the parotid function; it may also influence the salivery amylase activity, presumably by acting on the adenyl cyclase activity.

Original languageEnglish
Title of host publicationFluoride - Quarterly Reports
Pages217-223
Number of pages7
Volume17
Edition4
Publication statusPublished - 1984

Fingerprint

Parotid Gland
Amylases
Salivary Glands
Drinking Water
Fluorides
Isoproterenol
Saliva
Adenylyl Cyclases
Injections

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Effect of F- on major salivary glands. The amylase activity, stimulated salivary flow response and cAMP levels in parotid gland of rats consuming F- via drinking water. / Boros, I.; Mózsik, G.; Keszler, P.

Fluoride - Quarterly Reports. Vol. 17 4. ed. 1984. p. 217-223.

Research output: Chapter in Book/Report/Conference proceedingChapter

@inbook{8330b0c3e4b946cabad15876e8c9278b,
title = "Effect of F- on major salivary glands. The amylase activity, stimulated salivary flow response and cAMP levels in parotid gland of rats consuming F- via drinking water",
abstract = "This study examined the effect of intakes of 25 or 50 ppm fluoride via drinking water for four weeks on the amylase activity of the parotid gland, isoproterenol-stimulated (1 mg/100 g b.w., i.p.) salivary flow and on the amylase activity in saliva fractions. A significant elevation of the tissue amylase activity was seen in the F25 and F50 groups compared to control The volume of saliva collected for 30 min after isoproterenol injection was higher in the fluoride-treated groups; the amylase activity was also increased. In the glandular tissue cAMP level was augmented. It appears that fluoride may affect the parotid function; it may also influence the salivery amylase activity, presumably by acting on the adenyl cyclase activity.",
author = "I. Boros and G. M{\'o}zsik and P. Keszler",
year = "1984",
language = "English",
volume = "17",
pages = "217--223",
booktitle = "Fluoride - Quarterly Reports",
edition = "4",

}

TY - CHAP

T1 - Effect of F- on major salivary glands. The amylase activity, stimulated salivary flow response and cAMP levels in parotid gland of rats consuming F- via drinking water

AU - Boros, I.

AU - Mózsik, G.

AU - Keszler, P.

PY - 1984

Y1 - 1984

N2 - This study examined the effect of intakes of 25 or 50 ppm fluoride via drinking water for four weeks on the amylase activity of the parotid gland, isoproterenol-stimulated (1 mg/100 g b.w., i.p.) salivary flow and on the amylase activity in saliva fractions. A significant elevation of the tissue amylase activity was seen in the F25 and F50 groups compared to control The volume of saliva collected for 30 min after isoproterenol injection was higher in the fluoride-treated groups; the amylase activity was also increased. In the glandular tissue cAMP level was augmented. It appears that fluoride may affect the parotid function; it may also influence the salivery amylase activity, presumably by acting on the adenyl cyclase activity.

AB - This study examined the effect of intakes of 25 or 50 ppm fluoride via drinking water for four weeks on the amylase activity of the parotid gland, isoproterenol-stimulated (1 mg/100 g b.w., i.p.) salivary flow and on the amylase activity in saliva fractions. A significant elevation of the tissue amylase activity was seen in the F25 and F50 groups compared to control The volume of saliva collected for 30 min after isoproterenol injection was higher in the fluoride-treated groups; the amylase activity was also increased. In the glandular tissue cAMP level was augmented. It appears that fluoride may affect the parotid function; it may also influence the salivery amylase activity, presumably by acting on the adenyl cyclase activity.

UR - http://www.scopus.com/inward/record.url?scp=0021715233&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021715233&partnerID=8YFLogxK

M3 - Chapter

VL - 17

SP - 217

EP - 223

BT - Fluoride - Quarterly Reports

ER -