Effect of fluoride toothpastes on enamel demineralization

Wolfgang H. Arnold, Andreas Dorow, Stephanie Langenhorst, Zeno Gintner, Jolan Bánóczy, Peter Gaengler

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Background: It was the aim of this study to investigate the effect of four different toothpastes with differing fluoride compounds on enamel remineralization. Methods: A 3 x 3 mm window on the enamel surface of 90 human premolars was demineralized in a hydroxyethylcellulose solution at pH 4.8. The teeth were divided into 6 groups and the lower half of the window was covered with varnish serving as control. The teeth were immersed in a toothpaste slurry containing: placebo tooth paste (group 1); remineralization solution (group 2); Elmex Anticaries (group 3); Elmex Sensitive (group 4); Blend-a-med Complete (group 5) and Colgate GRF (group 6). Ten teeth of each group were used for the determination of the F- content in the superficial enamel layer and acid solubility of enamel expressed in soluble phosphorus. Of 6 teeth of each group serial sections were cut and investigated with polarization light microscopy (PLM) and quantitative energy dispersive X-ray analysis (EDX). Results: The PLM results showed an increased remineralization of the lesion body in the Elmex Anticaries, Elmex Sensitive and Colgate GRF group but not in the Blend-a-med group. A statistically significant higher Ca content was found in the Elmex Anticaries group. The fluoride content in the superficial enamel layer was significantly increased in both Elmex groups and the Blend-a-med group. Phosphorus solubility was significantly decreased in both Elmex groups and the Blend-a-med group. Conclusion: It can be concluded that amine fluoride compounds in toothpastes result in a clearly marked remineralization of caries like enamel lesions followed by sodium fluoride and sodium monofluorophosphate formulations.

Original languageEnglish
Article number8
JournalBMC Oral Health
Publication statusPublished - Jun 15 2006

ASJC Scopus subject areas

  • Dentistry(all)

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    Arnold, W. H., Dorow, A., Langenhorst, S., Gintner, Z., Bánóczy, J., & Gaengler, P. (2006). Effect of fluoride toothpastes on enamel demineralization. BMC Oral Health, 6, [8]. https://doi.org/10.1186/1472-6831-6-8