Az epilepsziás rohamok hatása a szívfrekvenciára.

Translated title of the contribution: Effect of epileptic seizures on the heart rate

Vanda Tóth, László Hejjel, Zsuzsanna Kalmár, András Fogarasi, Tibor Auer, Csilla Gyimesi, Anna Szucs, József Janszky

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

BACKGROUND: Sudden death appears in 8-17% of epilepsy patients non-responding to antiepileptic therapy. Some studies suggest that the most common cause of death is seizure-related cardiac arrhythmia. AIM OF STUDY: To analyze the alteration of the heart rate six hours before and after the seizures. METHODS: Eighteen patients suffering from focal epilepsy were examined before epilepsy surgery. Video-EEG-ECG was carried out for 2-10 days, and 32 seizures were registered. Analysis of the heart rate was based on the 5-minute-long epochs of the ECGs taken at the 5-10-15-30th minutes and at the 1-3-6th hours before and after seizures. RESULTS: The heart rate increases (from an average of 69 beats/min to 92 beats/min, p<0.001) immediately after seizures, though significantly higher heart rate was observed 3 hours after seizures. There were no patients with severe peri-ictal bradycardia. In one of our patients, ectopic cardiac rhythm occurred after a generalized tonic-clonic seizure. CONCLUSIONS: We can conclude that the sympathetic activity increases while the parasympathetic activity decreases after seizures. The observed alterations lasted for a long time and predict fatal arrhythmias. These suggest that sudden death in epilepsy can be induced by cardiac arrhythmias connected with epileptic seizures.

Original languageHungarian
Pages (from-to)155-161
Number of pages7
JournalIdeggyógyászati szemle
Volume61
Issue number5-6
Publication statusPublished - May 30 2008

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ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Tóth, V., Hejjel, L., Kalmár, Z., Fogarasi, A., Auer, T., Gyimesi, C., Szucs, A., & Janszky, J. (2008). Az epilepsziás rohamok hatása a szívfrekvenciára. Ideggyógyászati szemle, 61(5-6), 155-161.