Effect of different fractions of dialyzable leukocyte extract--transfer factor--on the chemiluminescence of human phagocytes.

S. Sipka, I. Schröder, N. A. Brazsnikova

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The chemiluminescence (CL) inducing effect of the fractions of dialyzable leukocyte extract (DLE)--transfer factor--from tonsil leukocytes was tested on the phagocytes of human whole blood. The fractionation of DLE by Sephadex G-25 results in three main fractions: I, II, III. We found only fraction II having a direct CL inducing effect on the non-stimulated cells. Fraction II increased further the CL of phagocytes which were stimulated by zymosan (Mannozym). Fractions I and III were ineffective. We suggest that in the complex "transfer factor" effects of DLE, the stimulation of the peripheral phagocytes of blood-by the oligopeptides of fraction II may have an important role.

Original languageEnglish
Pages (from-to)143-144
Number of pages2
JournalAllergologia et Immunopathologia
Volume15
Issue number3
Publication statusPublished - May 1987

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Transfer Factor
Phagocytes
Luminescence
Oligopeptides
Zymosan
Palatine Tonsil
Leukocytes

ASJC Scopus subject areas

  • Immunology and Allergy

Cite this

Effect of different fractions of dialyzable leukocyte extract--transfer factor--on the chemiluminescence of human phagocytes. / Sipka, S.; Schröder, I.; Brazsnikova, N. A.

In: Allergologia et Immunopathologia, Vol. 15, No. 3, 05.1987, p. 143-144.

Research output: Contribution to journalArticle

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