Effect of different dietary fumonisin B1 exposure on the toxin content of porcine tissues

Judit Fodor, Johann Bauer, Péter Horn, Ferenc Kovács, Melinda Kovács

Research output: Contribution to journalArticle

2 Citations (Scopus)


The time and dose-dependent effect of fumonisin B1 (FB 1) exposure on the tissue toxin concentrations was examined in 36 weaned pigs. Treated animals were fed an experimental diet supplemented with Fusarium verticillioides culture, leading to FB1 daily intake values of 50 mg/animal (n=10) in a 22 day treatment (T50), 100 mg/animal (n=7) for 5 days (T100s, short exposure) and 100 mg/animal (n=7) for 10 days (T100l, long exposure), respectively. For each experimental group, 4 control (C) animals were used. At the end of trial, the FB1 content of lung, liver, bile, kidney, brain, spleen, pancreas, heart, muscle and fat samples was determined by LC-MS. Pulmonary oedema developed in all piglets as a result of the toxin dose applied. Highest FB1 concentrations were found in the liver, kidney, lung and spleen, in all treatments. The muscle and adipose tissues (i.e. the meat) did not contain considerable amounts of fumonisin B1. In the organs of the animals fed 100 mg FB1 per day, significantly higher FB1 levels were measured. An exponential function was descriptive for the measured FB1 data of some organs. The FB1 content was found to be dependent on the average daily intake, except in case of the liver.

Original languageEnglish
Pages (from-to)73-78
Number of pages6
JournalItalian Journal of Animal Science
Issue numberSUPPL. 3
Publication statusPublished - Dec 1 2005


  • Feed contaminant
  • Fumonisin B
  • Mycotoxicosis
  • Pig

ASJC Scopus subject areas

  • Animal Science and Zoology

Fingerprint Dive into the research topics of 'Effect of different dietary fumonisin B<sub>1</sub> exposure on the toxin content of porcine tissues'. Together they form a unique fingerprint.

  • Cite this