Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers

P. Rafai, H. Pettersson, Á Bata, Z. Papp, R. Glávits, S. Tuboly, A. Ványi, P. Soós

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The effects of different dietary levels of T-2 toxin on production, biological, immunological, and pathological parameters of growing white Pekin ducks were studied to establish the "no effect" dietary concentration of, and "no effect" exposure time to, pure T-2 toxin. Day-old white Pekin ducks were randomly allotted to nine groups of 10 ducks each. One group served as a control, and no mycotoxin was added to its feed. The feeds of the experimental groups were supplemented with 0.2, 0.4, 0.6, 0.8, 1.0, 2.0, 3.0, and 4.0 mg purified T-2 toxin/kg, respectively, from Day 1 until Day 49 of the experiment. Dermatotoxic oral lesions developed in most experimental ducks within 2 d after the start of feeding T-2 toxin-contaminated feeds. The gradual disappearance of macroscopic signs indicated the development of tolerance in groups treated with the lower T-2 toxin content. No repair was found in the 3 and 4 mg/kg groups. Dietary concentrations of T-2 toxin below 0.4 mg/kg had no effect on the average weekly weight gain in the first 6 wk, but a severe decrease was found in the last week of the experiment. The 0.6 mg/kg dietary T-2 toxin had no effect on weight gain in the first 3 wk. At Week 4 and later, the weekly weight gain was significantly reduced, and the final live weight of this group was also significantly lower than that of the control. Dietary T-2 concentrations of 1 mg/kg and greater uniformly depressed growth rate. Only the 3 and 4 mg/kg groups refused feed during the first week. From Week 3 on, the feed intakes of the 0.6 to 4 mg/kg groups were usually less than that of the control group, indicating feed refusal. Serum and plasma chemical values and hematological parameters failed to show dose-dependent effects. The blastogenic response of lymphocytes to nonspecific and specific mitogens was distinctly impaired by the T-2 toxin at all levels in the feed. In the 3 and 4 mg/kg groups, the histological examination revealed lymphocyte depletion in the spleen and bursa of Fabricius.

Original languageEnglish
Pages (from-to)1548-1556
Number of pages9
JournalPoultry Science
Volume79
Issue number11
Publication statusPublished - Nov 2000

Fingerprint

Pekin
T-2 toxin
ducks
broiler chickens
weight gain
lymphocytes
biological production
feed contamination
bursa of Fabricius
lesions (animal)
mycotoxins
exposure duration
mouth
spleen
feed intake
body weight

Keywords

  • Dermatonecrosis
  • Duck
  • Immunity
  • T-2 toxin
  • Weight gain

ASJC Scopus subject areas

  • Animal Science and Zoology

Cite this

Rafai, P., Pettersson, H., Bata, Á., Papp, Z., Glávits, R., Tuboly, S., ... Soós, P. (2000). Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers. Poultry Science, 79(11), 1548-1556.

Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers. / Rafai, P.; Pettersson, H.; Bata, Á; Papp, Z.; Glávits, R.; Tuboly, S.; Ványi, A.; Soós, P.

In: Poultry Science, Vol. 79, No. 11, 11.2000, p. 1548-1556.

Research output: Contribution to journalArticle

Rafai, P, Pettersson, H, Bata, Á, Papp, Z, Glávits, R, Tuboly, S, Ványi, A & Soós, P 2000, 'Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers', Poultry Science, vol. 79, no. 11, pp. 1548-1556.
Rafai P, Pettersson H, Bata Á, Papp Z, Glávits R, Tuboly S et al. Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers. Poultry Science. 2000 Nov;79(11):1548-1556.
Rafai, P. ; Pettersson, H. ; Bata, Á ; Papp, Z. ; Glávits, R. ; Tuboly, S. ; Ványi, A. ; Soós, P. / Effect of dietary T-2 fusariotoxin concentrations on the health and production of white pekin duck broilers. In: Poultry Science. 2000 ; Vol. 79, No. 11. pp. 1548-1556.
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