Amniotic fluid samples were taken amniocentesis transabdominal aminocentesis from 22 pregnant women in the 32-37th gestation weeks. Determination of lecithin/sphingomyelin ration showed that in 20 cases the L/S ratio was 2 or less than 2. The patients were treated with i.m. dexamethasone in a total dose of 0.3 mg/kg body weight. Subsequently the L/S determination was repeated. Dexamethasone treatment resulted in a significat increase of L/S ratio. In 3 cases out of 22 the L/S ratio was below 2. No neonate developed RDS from this patient material. The authors are convinced that the risk of RDS is an indication for amniocentesis. If the L/S ratio equals 2 or is lower than this value, steroid prophylaxis is recommended.
|Translated title of the contribution||Effect of dexamethasone on lecithin sphingomyelin ratio in amniotic fluid|
|Number of pages||6|
|Journal||Zentralblatt fur Gynakologie|
|Publication status||Published - Jan 1 1978|
ASJC Scopus subject areas
- Obstetrics and Gynaecology