VERANDERUNGEN DES LEZITHIN-SPHINGOMYELIN-VERHALTNISSES IM FRUCHTWASSER AUF DEXAMETHASON-WIRKUNG

Translated title of the contribution: Effect of dexamethasone on lecithin sphingomyelin ratio in amniotic fluid

G. Nagy, Z. Hernadi, Z. Kardos, F. Ditroi

Research output: Contribution to journalArticle

Abstract

Amniotic fluid samples were taken amniocentesis transabdominal aminocentesis from 22 pregnant women in the 32-37th gestation weeks. Determination of lecithin/sphingomyelin ration showed that in 20 cases the L/S ratio was 2 or less than 2. The patients were treated with i.m. dexamethasone in a total dose of 0.3 mg/kg body weight. Subsequently the L/S determination was repeated. Dexamethasone treatment resulted in a significat increase of L/S ratio. In 3 cases out of 22 the L/S ratio was below 2. No neonate developed RDS from this patient material. The authors are convinced that the risk of RDS is an indication for amniocentesis. If the L/S ratio equals 2 or is lower than this value, steroid prophylaxis is recommended.

Translated title of the contributionEffect of dexamethasone on lecithin sphingomyelin ratio in amniotic fluid
Original languageGerman
Pages (from-to)583-588
Number of pages6
JournalZentralblatt fur Gynakologie
Volume100
Issue number9
Publication statusPublished - Jan 1 1978

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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