Vliianie snizheniiia krovotoka v pecheni na arterial'noe davlenie i na renin-angiotenzinovuiu sistemu krys.

Translated title of the contribution: Effect of decreased blood flow in the liver on blood pressure and on the renin-angiotensin system of the rat

S. Sonkodi, J. Kocsis, B. Tichy, V. Varró

Research output: Contribution to journalArticle

Abstract

The effect of reduced blood flow in the liver was studied in acute and chronic experiments on rats. 2 hours after partial constriction of the portal vein in anesthetized rats the mean blood pressure was lower and the plasma renin activity higher than in the control group. There was no relation between the two parameters. 20 weeks after partial constriction of the portal vein in unanesthetized animals the body weight, liver weight and serum albumin fraction were decreased, while the kidney weight was increased significantly and the heart weight insignificantly. The systolic blood pressure of these animals was found to be lower than that of the controls, and their blood pressure response to the i. v. administration of angiotensin II was also lower. In comparison with the control no significant differences were found in the blood renin and substrate levels. The natriuresis proved considerably lower in the animals with the partial constriction of the portal vein.

Original languageUndefined/Unknown
Pages (from-to)540-546
Number of pages7
JournalFiziologicheskii Zhurnal SSSR Imeni I.M. Sechenova
Volume69
Issue number4
Publication statusPublished - Apr 1983

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Renin-Angiotensin System
Portal Vein
Constriction
Blood Pressure
Liver
Weights and Measures
Angiotensinogen
Natriuresis
Renin
Serum Albumin
Angiotensin II
Body Weight
Kidney
Control Groups

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Vliianie snizheniiia krovotoka v pecheni na arterial'noe davlenie i na renin-angiotenzinovuiu sistemu krys. / Sonkodi, S.; Kocsis, J.; Tichy, B.; Varró, V.

In: Fiziologicheskii Zhurnal SSSR Imeni I.M. Sechenova, Vol. 69, No. 4, 04.1983, p. 540-546.

Research output: Contribution to journalArticle

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