Effect of cyclic AMP and polyadenylic acid treatment on the delayed hypersensitivity of guinea pigs

S. Sipka, J. Aradi, T. Szilagyi

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Abstract

Prolonged cAMP treatment was found to stimulate delayed hypersensitivity in the guinea pig. Continuous treatment with single stranded PolyA stimulated the delayed type of allergic dermatitis to a greater extent than did cAMP treatment representing an equal amount of adenylic acid. The possibility of desensitization in animals treated with cAMP or PolyA is similar. Both cAMP and PolyA were found to enhance the macrophage disappearance reaction.

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume20
Issue number3
Publication statusPublished - 1973

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Poly A
Delayed Hypersensitivity
Dermatitis
Adenosine Monophosphate
Cyclic AMP
Guinea Pigs
Macrophages

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "Prolonged cAMP treatment was found to stimulate delayed hypersensitivity in the guinea pig. Continuous treatment with single stranded PolyA stimulated the delayed type of allergic dermatitis to a greater extent than did cAMP treatment representing an equal amount of adenylic acid. The possibility of desensitization in animals treated with cAMP or PolyA is similar. Both cAMP and PolyA were found to enhance the macrophage disappearance reaction.",
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