Effect of combined treatment with aflatoxin B1and T-2 toxin and metabolites on some production traits and lipid peroxide status parameters of broiler chickens

László Pál, Károly Dublecz, Mária Kovács-Weber, Krisztián Balogh, Márta Erdélyi, Gábor Szigeti, Miklós Mézes

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Abstract

Three groups of cockerels were fed with a control diet, with a diet contaminated with T-2 and HT-2 toxin (0.31 and 0.26 mg/kg) or with that containing a combination of T-2 and HT-2 toxin (0.32 and 0.25 mg/kg) and aflatoxin B1(AFB1, 0.38 mg/kg) for 21 days. Body weight gain and feed conversion ratio did not differ significantly among the groups. Malondialdehyde concentration of the liver was lower in the group fed the diet contaminated with the combination of T-2 + HT-2 toxin and aflatoxin B1as compared to the control group or the group fed T-2 + HT-2 toxins. Reduced glutathione (GSH) content of the liver was lower in the T-2 + HT-2 group than in the group fed a combination of T-2, HT-2 and aflatoxin. Reduced glutathione content of the heart was higher in the T-2 + HT-2 group than in the control group. Mycotoxin contamination had no effect on glutathione peroxidase (GSH-Px) activity in comparison to the control, but significantly lower GSH-Px activity was found in the heart of chickens in the T-2 + HT-2 + AFB1group than in the T-2 + HT-2 group. In this study, T-2 + HT-2 toxin and aflatoxin B1contamination of the diets did not affect the production traits adversely and did not exert additive effects on lipid peroxidation and on the glutathione redox system.

Original languageEnglish
Pages (from-to)75-84
Number of pages10
JournalActa veterinaria Hungarica
Volume57
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

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Keywords

  • Aflatoxin B
  • Chicken
  • Glutathione
  • Glutathione peroxidase
  • Malondialdehyde
  • T-2 toxin

ASJC Scopus subject areas

  • veterinary(all)

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