Effect of combined neonatal imprinting by vitamin A, vitamin D3, benzpyrene and allylestrenol on adult rat thymus glucocorticoid and uterine estrogen receptors

G. Csaba, Á Inczefi-Gonda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

1. Combined neonatal imprinting with allylestrenol, vitamins A and D3 and benzpyrene significantly increased thymic glucocorticoid receptor capacity in male and female animals and decreased receptors affinity in adult females only. 2. Uterine estrogen receptor affinity or density was not influenced. 3. Considering that perinatal treatment with allylestrenol or vitamin D3 decreased glucocorticoid receptor capacity, the dominance of the positive effect of retinol should be surmised. 4. The experiments call attention to the interrelation of different materials acting simultaneously in the perinatal period.

Original languageEnglish
Pages (from-to)779-781
Number of pages3
JournalGeneral Pharmacology
Volume29
Issue number5
DOIs
Publication statusPublished - Nov 1 1997

Keywords

  • Allyesterenol
  • Benzo(a)pyrene
  • Hormonal imprinting
  • Hormone receptors
  • Neontal imprinting
  • Vitamin A
  • Vitamin D

ASJC Scopus subject areas

  • Pharmacology

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