Effect of clinical duration of diabetes mellitus on various antioxidants in blood

J. Prechl, E. Szaleczky, P. Pusztai, I. Kocsis, Z. Tulassay, A. Somogyi

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The authors examined 15 healthy (group 0) and 42 diabetic subjects (groups 1 and 2) with the goal of investigating the relationships between the duration of diabetes and various measures of antioxidant activity in blood. The diabetics were divided into two groups on the basis of duration of diabetes: 25 patients suffered from diabetes for less than 10 years (group 1), 17 of them had diabetes for a longer period of time (group 2). The ratio of type I: type II diabetics was 8:17 and 3:14 in group 1 and 2, respectively. Clinical chemistry revealed that serum glucose, HbA1c concentration and atherogenic index were significantly elevated in the both diabetic groups. Among the antioxidants the measured erythrocyte superoxide dismutase (SOD) and plasma Total Antioxidant Status (TAS) were significantly reduced in group 2 as compared to group 1, while the activities of whole blood glutathione peroxidase (Gpx) and erythrocyte catalase (CAT) did not differ. A significant negative correlation (r=-0.33, p

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalMedical Science Monitor
Volume3
Issue number2
Publication statusPublished - 1997

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Diabetes Mellitus
Antioxidants
Erythrocytes
Clinical Chemistry
Glutathione Peroxidase
Catalase
Superoxide Dismutase
Glucose
Serum

Keywords

  • Antioxidant status
  • Diabetes mellitus
  • Duration of diabetes
  • Oxidative stress
  • Superoxide dismutase

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Effect of clinical duration of diabetes mellitus on various antioxidants in blood. / Prechl, J.; Szaleczky, E.; Pusztai, P.; Kocsis, I.; Tulassay, Z.; Somogyi, A.

In: Medical Science Monitor, Vol. 3, No. 2, 1997, p. 167-170.

Research output: Contribution to journalArticle

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