Abstract
Antioxidant nomination covers a substance group of great variety, therefore, the determination of action mechanism of new antioxidants requires a complicated test system. The present work demonstrates this labour and time consuming procedure conducted on human red blood cells (RBCs) exposing them to "stress effect" with diluted hydrogen peroxide. It was studied how did these oxidative stress conditions affect the filtration parameters, lipid peroxidation, reduced glutathione content and superoxide dismutase activity of RBCs. It was attempted to reverse or influence the significant changes caused by "oxidative stress" with known antioxidants (vitamin E and uric acid).
| Original language | Hungarian |
|---|---|
| Pages (from-to) | 2863-2864, 2867 |
| Journal | Orvosi Hetilap |
| Volume | 132 |
| Issue number | 51 |
| Publication status | Published - Dec 23 1991 |
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ASJC Scopus subject areas
- Medicine(all)
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Antioxidánsok hatása a vörösvértest oxidatív stressre. / Varga, I.; Novák, Z.; Matkovics, B.; Patocskai, M.
In: Orvosi Hetilap, Vol. 132, No. 51, 23.12.1991, p. 2863-2864, 2867.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidánsok hatása a vörösvértest oxidatív stressre.
AU - Varga, I.
AU - Novák, Z.
AU - Matkovics, B.
AU - Patocskai, M.
PY - 1991/12/23
Y1 - 1991/12/23
N2 - Antioxidant nomination covers a substance group of great variety, therefore, the determination of action mechanism of new antioxidants requires a complicated test system. The present work demonstrates this labour and time consuming procedure conducted on human red blood cells (RBCs) exposing them to "stress effect" with diluted hydrogen peroxide. It was studied how did these oxidative stress conditions affect the filtration parameters, lipid peroxidation, reduced glutathione content and superoxide dismutase activity of RBCs. It was attempted to reverse or influence the significant changes caused by "oxidative stress" with known antioxidants (vitamin E and uric acid).
AB - Antioxidant nomination covers a substance group of great variety, therefore, the determination of action mechanism of new antioxidants requires a complicated test system. The present work demonstrates this labour and time consuming procedure conducted on human red blood cells (RBCs) exposing them to "stress effect" with diluted hydrogen peroxide. It was studied how did these oxidative stress conditions affect the filtration parameters, lipid peroxidation, reduced glutathione content and superoxide dismutase activity of RBCs. It was attempted to reverse or influence the significant changes caused by "oxidative stress" with known antioxidants (vitamin E and uric acid).
UR - http://www.scopus.com/inward/record.url?scp=0026430636&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026430636&partnerID=8YFLogxK
M3 - Article
C2 - 1762765
AN - SCOPUS:0026430636
VL - 132
SP - 2863-2864, 2867
JO - Orvosi Hetilap
JF - Orvosi Hetilap
SN - 0030-6002
IS - 51
ER -