Effect of acute selenium toxicosis on the lipid peroxide status and the glutathione system of broiler chickens.

M. Mézes, G. Sályi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The effect of acute oral selenium toxicosis on the rate of lipid peroxidation, on the amount of reduced glutathione as well as on glutathione-peroxidase activity of the blood (plasma and red blood cells) and liver was studied in broiler chicken. Cockerels (28-day-old) were treated with selenium (4.85 mg/kg b.w.) administered intraoesophageally in the form of sodium selenite. Samples were at the onset of clinical signs (3 h after treatment) and 2 and 4 h thereafter. The malondialdehyde content of the blood plasma rose significantly (P <0.05) at the onset of clinical symptoms but decreased later. Malondialdehyde content of the liver was higher than the control value at the first sampling (P <0.01) and steadily increased later. Reduced glutathione content did not change significantly in the blood plasma and liver. Glutathione peroxidase activity of the RBC was significantly elevated (P <0.01) only at the first sampling (3 h after treatment) and decreased to the control level thereafter. Acute oral selenium toxicosis increases the rate of lipid peroxidation in a short period of time (7 h) without exerting a significant effect on the glutathione system.

Original languageEnglish
Pages (from-to)459-463
Number of pages5
JournalActa Veterinaria Hungarica
Volume42
Issue number4
Publication statusPublished - 1994

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Lipid Peroxides
Selenium
peroxides
blood plasma
selenium
Glutathione
poisoning
glutathione
Chickens
broiler chickens
Glutathione Peroxidase
Malondialdehyde
glutathione peroxidase
malondialdehyde
liver
Lipid Peroxidation
Liver
mouth
lipid peroxidation
erythrocytes

ASJC Scopus subject areas

  • veterinary(all)

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Effect of acute selenium toxicosis on the lipid peroxide status and the glutathione system of broiler chickens. / Mézes, M.; Sályi, G.

In: Acta Veterinaria Hungarica, Vol. 42, No. 4, 1994, p. 459-463.

Research output: Contribution to journalArticle

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