Effect of a single early-gestational alcohol consumption on the insulin binding by immune cells of adult rats

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6 Citations (Scopus)

Abstract

Rat dams were exposed to 15 % ethanol containing water ad libitum for 24 h at the 3rd day of gestation. Adult progenies' immune cells (peritoneal, blood and thymic lymphocytes, monocyte-macrophage-granulocyte group and mast cells) were studied by flow cytometry for binding of FITC-labelled insulin (compared to the appropriate cells of untreated animals). All of the cell types studied bound significantly less insulin, except mast cells. The results call attention to the life-long effect of occasional alcohol consumption in early pregnancy manifested in the immune system.

Original languageEnglish
Pages (from-to)483-484
Number of pages2
JournalInflammation Research
Volume54
Issue number12
DOIs
Publication statusPublished - Dec 1 2005

Keywords

  • Alcohol
  • Immune cells
  • Insulin binding
  • Pregnancy

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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