Effect of a nitric oxide donor on nitroxergic nerve fibers in the rat dura mater

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the anterior and middle meningeal arteries, and the sinus sagittalis superior. Structural alterations of nitroxergic axons innervating blood vessels of the dura mater support the idea that nitric oxide is involved in the induction of headache also by a primary peripheral action, a well-known side effect of coronary dilator agents.

Original languageEnglish
Pages (from-to)97-100
Number of pages4
JournalNeuroscience Letters
Volume260
Issue number2
DOIs
Publication statusPublished - Jan 29 1999

Fingerprint

Dura Mater
Nitric Oxide Donors
Nerve Fibers
Nitric Oxide Synthase
Meningeal Arteries
Superior Sagittal Sinus
Nitroglycerin
Blood Vessels
Headache
Axons
Nitric Oxide
Body Weight

Keywords

  • Dura mater
  • Immunohistochemistry
  • Migraine headache
  • Nitric oxide synthase
  • Nitroglycerine

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effect of a nitric oxide donor on nitroxergic nerve fibers in the rat dura mater. / Knyihár-Csillik, E.; Vécsei, L.

In: Neuroscience Letters, Vol. 260, No. 2, 29.01.1999, p. 97-100.

Research output: Contribution to journalArticle

@article{8b50745b75264fb88748ae2fbcb299e4,
title = "Effect of a nitric oxide donor on nitroxergic nerve fibers in the rat dura mater",
abstract = "Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the anterior and middle meningeal arteries, and the sinus sagittalis superior. Structural alterations of nitroxergic axons innervating blood vessels of the dura mater support the idea that nitric oxide is involved in the induction of headache also by a primary peripheral action, a well-known side effect of coronary dilator agents.",
keywords = "Dura mater, Immunohistochemistry, Migraine headache, Nitric oxide synthase, Nitroglycerine",
author = "E. Knyih{\'a}r-Csillik and L. V{\'e}csei",
year = "1999",
month = "1",
day = "29",
doi = "10.1016/S0304-3940(98)00949-5",
language = "English",
volume = "260",
pages = "97--100",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

TY - JOUR

T1 - Effect of a nitric oxide donor on nitroxergic nerve fibers in the rat dura mater

AU - Knyihár-Csillik, E.

AU - Vécsei, L.

PY - 1999/1/29

Y1 - 1999/1/29

N2 - Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the anterior and middle meningeal arteries, and the sinus sagittalis superior. Structural alterations of nitroxergic axons innervating blood vessels of the dura mater support the idea that nitric oxide is involved in the induction of headache also by a primary peripheral action, a well-known side effect of coronary dilator agents.

AB - Nitroglycerine, given subcutaneously to rats (10 mg/kg body weight) induces increased beading of nitric oxide synthase immunoreactive (NOS-IR) nerve fibers in the supratentorial cerebral dura mater, and an apparent increase in the number of NOS-IR nerve fibers in the dural areas supplied by the anterior and middle meningeal arteries, and the sinus sagittalis superior. Structural alterations of nitroxergic axons innervating blood vessels of the dura mater support the idea that nitric oxide is involved in the induction of headache also by a primary peripheral action, a well-known side effect of coronary dilator agents.

KW - Dura mater

KW - Immunohistochemistry

KW - Migraine headache

KW - Nitric oxide synthase

KW - Nitroglycerine

UR - http://www.scopus.com/inward/record.url?scp=0033613749&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033613749&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(98)00949-5

DO - 10.1016/S0304-3940(98)00949-5

M3 - Article

C2 - 10025708

AN - SCOPUS:0033613749

VL - 260

SP - 97

EP - 100

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 2

ER -