Effect of a coronary vasodilator drug (carbochromen) on blood flow and oxygen extraction in acute myocardial infarction

J. Parratt, I. Mca Ledingham, C. S. Mcardle

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

AUTHORS' SYNOPSIS: Blood flow was measured in acute myocardial infarcts in dogs using a 133Xenon clearance technique. Simultaneous sampling of blood from a vein draining the infarct enabled assessments to be made of oxygen extraction and consumption. Flow and consumption were also measured in normal areas of myocardium. Carbochromen, though increasing flow in normal areas of myocardium, failed to increase flow in the infarct but oxygen extraction and consumption were reduced.

Original languageEnglish
Pages (from-to)401-407
Number of pages7
JournalCardiovascular Research
Volume7
Issue number3
DOIs
Publication statusPublished - May 1973

Fingerprint

Chromonar
Acute Myocardial Infarction
Blood Flow
Vasodilator Agents
Oxygen Consumption
Oxygen
Myocardium
Drugs
Blood
Myocardial Infarction
Veins
Dogs
Clearance
Sampling
Acute
Acute myocardial infarction

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Effect of a coronary vasodilator drug (carbochromen) on blood flow and oxygen extraction in acute myocardial infarction. / Parratt, J.; Ledingham, I. Mca; Mcardle, C. S.

In: Cardiovascular Research, Vol. 7, No. 3, 05.1973, p. 401-407.

Research output: Contribution to journalArticle

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