Effect of 3-methylcholanthrene on RNA polymerase and protein kinase activities of transcriptionally active chromatin subfraction in rat liver

J. Szeberényi, U. Kleeberg, A. Tigyi

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Abstract

The activities of RNA polymerases and nuclear protein kinases were determined in subfractions of rat liver nuclei after a single dose of the polycyclic aromatic hydrocarbon 3-methylcholanthrene (3-MC). Both enzyme activities as well as the in vivo phosphorylation of chromatin proteins were enhanced by 3-MC in the transcriptionally active subfraction of chromatin.

Original languageEnglish
Pages (from-to)687-689
Number of pages3
JournalExperientia
Volume38
Issue number6
DOIs
Publication statusPublished - Jun 1 1982

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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