Ecdysteroids from Serratula wolffii roots

Erika Liktor-Busa, András Simon, Gábor Tóth, Gábor Fekete, Zoltán Kele, Mária Báthori

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12 Citations (Scopus)

Abstract

Two new natural ecdysteroids, 20,22-didehydrotaxisterone (1) and 1-hydroxy-20,22-didehydrotaxisterone (2), were isolated from the roots of Serratula wolffii. Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry. The biological activities of these compounds were determined via oral aphid (Acyrthosiphon pisum (Harris)) tests. Compound 1 was inactive and compound 2 exhibited very low toxicity in the oral aphid test. The activities of these two ecdysteroids were in agreement with those of other 22-deoxyecdysteroids.

Original languageEnglish
Pages (from-to)884-886
Number of pages3
JournalJournal of Natural Products
Volume70
Issue number5
DOIs
Publication statusPublished - May 1 2007

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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