Early enteral nutrition in acute pancreatitis-benefits and limitations

Attila Oláh, László Romics

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Introduction: The application of enteral feeding as part of the treatment of acute pancreatitis goes back more than a decade now. In this review, the authors outline the indications and limitations of enteral feeding in the treatment of acute pancreatitis using up-to-date evidence-based data. Results and discussion: Latest meta-analyses suggest that early enteral feeding reduces effectively the incidence of infective complications and shortens hospital stay. In addition, recently published randomized controlled trials indicate that it may reduce mortality as well. Conclusion: However, the role of immune-enhancing ingredients, such as glutamine or ω-3 fatty acids, combined with enteral nutrition is uncertain, and the published studies are too few to make any treatment recommendation. Supplementation of enteral feeding with probiotics is a potentially promising alternative, but further well-designed multi-centric trials are necessary to prove their role in the treatment of acute pancreatitis.

Original languageEnglish
Pages (from-to)261-269
Number of pages9
JournalLangenbeck's Archives of Surgery
Volume393
Issue number3
DOIs
Publication statusPublished - May 1 2008

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Keywords

  • Acute pancreatitis
  • Enteral nutrition
  • Immunonutrition
  • Probiotics

ASJC Scopus subject areas

  • Surgery

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