Incidence of prostate cancer has increased significantly in the past ten years worldwide. However, thanks to extensive pathological investigations major process can be witnessed in early recognition. Pathologists and urologists have been researching what sort of premalignant changes can be detected in the structure of the tissue of the prostate prior to the appearance of the carcinoma. Characteristics of prostatic intraepithelial neoplasia (PIN) seems to be accepted as precursor of prostate carcinoma. Examinations refer to that untreated prostate intraepithelial neoplasia tends to develop into early prostate cancer although this assumption has been supported only by indirect examination signs. There is neither reference to PIN from PSA value nor ultrasound abnormalities can be detected in the course of transrectal ultrasound examinations. Authors sum up PIN cases found among their own biopsy materials and call attention to the importance of early recognition of prostate cancer.
|Number of pages||7|
|Publication status||Published - Jan 1 2000|
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