Early developmental characteristics and features of major depressive disorder among child psychiatric patients in Hungary

K. Kapornai, Amy L. Gentzler, Ping Tepper, E. Kiss, László Mayer, Z. Tamás, Maria Kovacs, A. Vetró

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: We investigate the relations of early atypical characteristics (perinatal problems, developmental delay, and difficult temperament) and onset-age (as well as severity of) first major depressive disorder (MDD) and first internalizing disorder in a clinical sample of depressed children in Hungary. Method: Participants were 371 children (ages 7-14) with MDD, and their biological mothers, recruited through multiple clinical sites. Diagnoses (via DSM-IV criteria) and onset dates of disorders were finalized "best estimate" psychiatrists, and based on multiple information sources. Mothers provided developmental data in a structured interview. Results: Difficult temperament predicted earlier onset of MDD and first internalizing disorder, but its effect was ameliorated if the family was intact during early childhood. Further, the importance of difficult temperament decreased as a function of time. Perinatal problems and developmental delay did not impact onset ages of disorders, and none of the early childhood characteristics associated with MDD episode severity. Conclusions: Children with MDD may have added disadvantage of earlier onset if they had a difficult temperament in infancy. Because early temperament mirrors physiological reactivity and regulatory capacity, it can affect various areas of functioning related to psychopathology. Early caregiver stability may attenuate some adverse effects of difficult infant temperament.

Original languageEnglish
Pages (from-to)91-101
Number of pages11
JournalJournal of Affective Disorders
Volume100
Issue number1-3
DOIs
Publication statusPublished - Jun 2007

Fingerprint

Child Psychiatry
Temperament
Hungary
Major Depressive Disorder
Age of Onset
Mothers
Psychopathology
Diagnostic and Statistical Manual of Mental Disorders
Caregivers
Psychiatry
Interviews

Keywords

  • Age of onset
  • Childhood characteristics
  • Depression
  • Intact family
  • Temperament

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Early developmental characteristics and features of major depressive disorder among child psychiatric patients in Hungary. / Kapornai, K.; Gentzler, Amy L.; Tepper, Ping; Kiss, E.; Mayer, László; Tamás, Z.; Kovacs, Maria; Vetró, A.

In: Journal of Affective Disorders, Vol. 100, No. 1-3, 06.2007, p. 91-101.

Research output: Contribution to journalArticle

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