Dual labeling of biomolecules by using click chemistry: A sequential approach

P. Kele, G. Mező, Daniela Achatz, Otto S. Wolfbeis

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

(Figure Presented) Click by click: Dual labeling of model compounds was carried out by using copper-free and copper-mediated click chemistry in a sequential manner. This method was used to introduce two labels onto biological targets or nanoparticles, thus quickly converting them into fluorescence resonance energy transfer systems.

Original languageEnglish
Pages (from-to)344-347
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number2
DOIs
Publication statusPublished - Jan 2 2009

Fingerprint

Biomolecules
Labeling
Copper
Labels
Nanoparticles
Fluorescence Resonance Energy Transfer

Keywords

  • Click chemistry
  • Copper
  • FRET
  • Peptides

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Dual labeling of biomolecules by using click chemistry : A sequential approach. / Kele, P.; Mező, G.; Achatz, Daniela; Wolfbeis, Otto S.

In: Angewandte Chemie - International Edition, Vol. 48, No. 2, 02.01.2009, p. 344-347.

Research output: Contribution to journalArticle

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