DSC examination of kidney tissue following warm ischemia and reperfusion injury

Andrea Ferencz, Klára Nedvig, Eszter László, Tamás Magyarlaki, Dénes Lrinczy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The fact that kidney is sensitive to ischemia/reperfusion (I/R) injury had encouraged us to compare the conventional histology and differential scanning calorimetry (DSC) methods in renal structural changes following experimental warm I/R models. Our histological findings showed that longer warm I/R period caused more severe damage in structure of kidney. The thermal parameters (transition temperature, calorimetric enthalpy) of I/R injury reflected the histological results. These processes correlated with the ischemia time and the degree of injury was more serious after reperfusion periods compared to normal kidney structure, which provides basis for further investigation in different kidney stress models.

Original languageEnglish
Pages (from-to)161-166
Number of pages6
JournalThermochimica Acta
Volume525
Issue number1-2
DOIs
Publication statusPublished - Oct 20 2011

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Keywords

  • DSC
  • Kidney
  • Tissue injury
  • Warm ischemia/reperfusion

ASJC Scopus subject areas

  • Instrumentation
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

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