Méhnyakdaganatok képvezérelt adaptív intersticiális-intrakavitális brahiterápiájának dozimetriai elemzése és a hagyományos kezelési technikákkal való összehasonlítása

Translated title of the contribution: Dosimetric evaluation of intracavitary-interstitial image-guided adaptive brachytherapy of cervical cancer and comparison with conventional treatment techniques

Georgina Fröhlich, Júlia Vízkeleti, Nguyen Anhhong Nhung, Katalin Horváth, Tibor Major, Csaba Polgár

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Our aim was the dosimetric evaluation of intracavitary-interstitial high-dose-rate image-guided adaptive cervix brachytherapy, implemented in Hungary. Between 2016 and 2018, 21 patients with cervical cancer were treated with overall 72 fractions. Graphical optimized treatment plans were compared to inverse optimized plans, 3D optimized plans (without needles) and conventional intracavitary 2D plans. Significant difference was found in almost all dose-volume parameters. The most advantageous values came from interstitial plans, inverse optimized plans did not differ dosimetrically from the treatment plans, while intracavitary optimized plans disposed of less appropriate dose-volume parameters, the least of all were intracavitary 2D plans. Needle number showed correlation with conformality, but inverse correlation with Dose Nonuniformity Ratio and D2cm3 of rectum. Volume of High Risk CTV correlated with D2cm3 of bladder, rectum and sigmoid. Although 3D optimization improved the quality of conventional 2D plans, interstitial plans resulted in even more homogeneous dose distribution and significantly lower doses to organs at risks.

Translated title of the contributionDosimetric evaluation of intracavitary-interstitial image-guided adaptive brachytherapy of cervical cancer and comparison with conventional treatment techniques
Original languageHungarian
Pages (from-to)242-248
Number of pages7
JournalMagyar onkologia
Volume62
Issue number4
Publication statusPublished - Dec 12 2018

ASJC Scopus subject areas

  • Medicine(all)

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