Az axilláris nyirokcsomók dózisa különféle besugárzási mezõelrendezésekbõl emlõmegtartó mûtét után

Translated title of the contribution: Dose coverage of axillary target volumes using different field arrangements following breast conserving surgery for invasive breast cancer

Bence Bukovszky, J. Fodor, Zsuzsánna Zongor, Dalma Mihály, Zoltán Mátrai, C. Polgár, T. Major

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to investigate the dose coverage of sentinel lymph node (SLN) site, level I, II and III axillary target volumes using different field arrangements (standard or high tangent fields: STgF, HTgF and STgF + axillary-supraclavicular field: ASF) in N0 invasive breast cancer patients treated with breast conserving surgery. In 30 patients the SLN site was marked with titanium clip. They were treated with 3D-conformal radiotherapy. Retrospectively, for the purpose of this study, the SLN site and axillary target volumes were contoured, and three plans were generated for each patient using the original CT data. The prescribed dose was 50 Gy (2 Gy/fraction). The mean dose with STgF or HTgF was 33.1 and 49.1 Gy (p=0.0001) in the SLN site, 25.7 and 45.1 Gy (p<0.0001) in level I, 7.2 and 28.9 Gy (p<0.0001) in level II and 3.5 and 12.7 Gy (p=0.0003) in level III. The mean dose with STgF+ASF in level II or III was 45 and 46 Gy. The dose coverage is inadequate to all axillary levels with STgM. The target volumes should be delineated to give accurate dose estimation.

Original languageHungarian
Pages (from-to)103-110
Number of pages8
JournalMagyar onkologia
Volume64
Issue number2
Publication statusPublished - Jun 21 2019

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Segmental Mastectomy
Breast Neoplasms
Conformal Radiotherapy
Titanium
Surgical Instruments
Sentinel Lymph Node

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Az axilláris nyirokcsomók dózisa különféle besugárzási mezõelrendezésekbõl emlõmegtartó mûtét után. / Bukovszky, Bence; Fodor, J.; Zongor, Zsuzsánna; Mihály, Dalma; Mátrai, Zoltán; Polgár, C.; Major, T.

In: Magyar onkologia, Vol. 64, No. 2, 21.06.2019, p. 103-110.

Research output: Contribution to journalArticle

Bukovszky, Bence ; Fodor, J. ; Zongor, Zsuzsánna ; Mihály, Dalma ; Mátrai, Zoltán ; Polgár, C. ; Major, T. / Az axilláris nyirokcsomók dózisa különféle besugárzási mezõelrendezésekbõl emlõmegtartó mûtét után. In: Magyar onkologia. 2019 ; Vol. 64, No. 2. pp. 103-110.
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abstract = "The purpose of this study was to investigate the dose coverage of sentinel lymph node (SLN) site, level I, II and III axillary target volumes using different field arrangements (standard or high tangent fields: STgF, HTgF and STgF + axillary-supraclavicular field: ASF) in N0 invasive breast cancer patients treated with breast conserving surgery. In 30 patients the SLN site was marked with titanium clip. They were treated with 3D-conformal radiotherapy. Retrospectively, for the purpose of this study, the SLN site and axillary target volumes were contoured, and three plans were generated for each patient using the original CT data. The prescribed dose was 50 Gy (2 Gy/fraction). The mean dose with STgF or HTgF was 33.1 and 49.1 Gy (p=0.0001) in the SLN site, 25.7 and 45.1 Gy (p<0.0001) in level I, 7.2 and 28.9 Gy (p<0.0001) in level II and 3.5 and 12.7 Gy (p=0.0003) in level III. The mean dose with STgF+ASF in level II or III was 45 and 46 Gy. The dose coverage is inadequate to all axillary levels with STgM. The target volumes should be delineated to give accurate dose estimation.",
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