Does the membrane's physical state control the expression of heat shock and other genes?

L. Vígh, Bruno Maresca, John L. Harwood

Research output: Contribution to journalArticle

301 Citations (Scopus)

Abstract

Membranes provide the structural framework that divides cells from their environment and that, in eukaryotic cells, permits compartmentation. They are not simply passive barriers that are liable to be damaged during environmental challenge or pathological states, but are involved in cellular responses and in modulating intracellular signalling. Recent data show that the expression of several genes, particularly those that respond to changes in temperature, ageing or disease, is influenced and/or controlled by the membrane's physical state. Copyright (C) 1998 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)369-374
Number of pages6
JournalTrends in Biochemical Sciences
Volume23
Issue number10
DOIs
Publication statusPublished - Oct 1 1998

Fingerprint

Cell Compartmentation
Shock
Hot Temperature
Genes
Membranes
Eukaryotic Cells
Aging of materials
Gene Expression
Temperature

ASJC Scopus subject areas

  • Biochemistry

Cite this

Does the membrane's physical state control the expression of heat shock and other genes? / Vígh, L.; Maresca, Bruno; Harwood, John L.

In: Trends in Biochemical Sciences, Vol. 23, No. 10, 01.10.1998, p. 369-374.

Research output: Contribution to journalArticle

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