Does obstetric brachial plexus injury influence speech dominance?

Tibor Auer, Sandor Pinter, Norbert Kovacs, Zsuzsanna Kalmar, Ferenc Nagy, Reka A. Horvath, Balazs Koszo, Gyula Kotek, Gabor Perlaki, Maria Koves, Bernadette Kalman, Samuel Komoly, Attila Schwarcz, Friedrich G. Woermann, Jozsef Janszky

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Objective: Right-handedness and left-sided language lateralization is an unresolved mystery with unknown cause/effect relations. Most studies suggest that the language lateralization is related to a fundamental brain asymmetry: right-handedness may be secondary. We analyzed the possibility of an opposite cause/effect relation: whether asymmetric hand usage (as a cause) can influence language lateralization (as a consequence). Methods: We determined language lateralization by functional magnetic resonance imaging in 15 subjects whose upper limb (UL) had been injured at birth because of unilateral damage of the brachial plexus. These subjects were able to use only one (the noninjured) UL perfectly. Results: We found correlation between the severity of right-sided UL injuries and hand usage dysfunction and the degree of left-to-right shift of language lateralization. There was, however, not a complete switch of language lateralization. Interpretation: Right-sided UL injury can induce a left-to-right shift in language lateralization, suggesting that hand usage can influence language lateralization. These findings may contradict the broadly accepted theory that right-handedness is a secondary phenomenon caused by left-sided hemispheric language lateralization. However, the cause/effect problem between asymmetric hand usage and language lateralization is not resolved in this study. Our findings may support the theory that gestures had a crucial role in human language evolution and is a part of the language system even today.

Original languageEnglish
Pages (from-to)57-66
Number of pages10
JournalAnnals of Neurology
Volume65
Issue number1
DOIs
Publication statusPublished - Jan 1 2009

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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  • Cite this

    Auer, T., Pinter, S., Kovacs, N., Kalmar, Z., Nagy, F., Horvath, R. A., Koszo, B., Kotek, G., Perlaki, G., Koves, M., Kalman, B., Komoly, S., Schwarcz, A., Woermann, F. G., & Janszky, J. (2009). Does obstetric brachial plexus injury influence speech dominance? Annals of Neurology, 65(1), 57-66. https://doi.org/10.1002/ana.21538