¿Provoca la dermatitis herpetiforme pérdida ósea al igual que la enfermedad celiaca? Un estudio transversal

Translated title of the contribution: Does dermatitis herpetiformis result in bone loss as coeliac disease does? A cross sectional study

Katalin Lorinczy, Márk Juhász, Ágnes Csontos, Bálint Fekete, Orsolya Terjék, Péter L. Lakatos, Pál Miheller, Dorottya Kocsis, Sarolta Kárpáti, Zsolt Tulassay, Tamás Zágoni

Research output: Contribution to journalArticle

6 Citations (Scopus)


Introduction and objectives: Coeliac disease (CD) and its cuta-neous manifestation, dermatitis herpetiformis are both (DH) gluten-sensitive diseases. Metabolic bone disease is common among patients with CD, even in asymptomatic forms. Data are scarce about bone density in patients with dermatitis herpetiformis. The aim of our study was to compare bone mineral density (BMD) of celiac and der-matitis herpetiformis patients. Methods: 34 coeliac patients, 53 with dermatitis herpetiformis and 42 healthy controls were studied. The mean age was 38.0 ± 12.1, 32.18 ± 14.95, 35.33 ± 10.41 years in CD, dermatitis herpetiformis, and healthy controls, respectively. Bone mineral density of the lumbar spine, the left femoral neck and radius were measured by dual-energy X-ray absorptiometry. Low bone density, osteopenia and osteoporosis were defined as a body mass density (BMD) T-score between 0 and -1, between -1 and -2.5, and under -2.5, respectively. Results: at lumbar region, consisting of dominantly trabecular compartment, a decreased BMD was detected in 49 % (n = 26) patients with dermatitis herpetiformis, 62 % (n = 21) of CD patients, and 29 % (n = 12) of healthy controls, respectively. Lower BMD were measured at the lumbar region in dermatitis herpetiformis and CD compared to healthy subjects (0.993 ± 0.136 g/cm 2and 0.880 ± 0.155 g/cm 2 vs. 1.056 ± 0.126 g/cm 2; p < 0.01). Density of bones consisting of dominantly cortical compartment (femoral neck) did not differ in dermatitis herpetiformis and healthy subjects. Conclusions: our results show that a low bone mass is also fre-quent among patients with dermatitis herpetiformis. Bone mineral content in these patients is significantly lower in those parts of the skeleton which contain more trabecular than cortical bone.

Translated title of the contributionDoes dermatitis herpetiformis result in bone loss as coeliac disease does? A cross sectional study
Original languageSpanish
Pages (from-to)187-193
Number of pages7
JournalRevista Espanola de Enfermedades Digestivas
Issue number4
Publication statusPublished - Mar 2013


  • Bone mineral density
  • Coeliac disease
  • Dermatitis herpetiformis
  • Osteoporosis

ASJC Scopus subject areas

  • Gastroenterology

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