DNA sequence of frog adenovirus

A. J. Davison, K. M. Wright, B. Harrach

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

The genome of frog adenovirus (FrAdV-1) was sequenced and found to be the smallest of all known adenovirus genomes. The sequence obtained was 26163 bp in size and contains a substantial direct repeat near the right terminus, implying that it was derived by recombination from a parental genome of only 25517 bp. The closest relative of FrAdV-1 proved to be turkey adenovirus 3, an avian adenovirus with no previously known near relative. Sequence comparisons showed that the two viruses have equivalent gene complements, including one gene the product of which is related to sialidases. Phylogenetic analyses supported the establishment of a fourth adenovirus genus containing these two viruses, in addition to the established genera Mastadenovirus and Aviadenovirus and the proposed genus Atadenovirus. Sixteen genes were identified as being conserved between these four lineages and were presumably inherited from an ancestral adenovirus.

Original languageEnglish
Pages (from-to)2431-2439
Number of pages9
JournalJournal of General Virology
Volume81
Issue number10
Publication statusPublished - 2000

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Siadenovirus
Aviadenovirus
Adenoviridae
Genome
Mastadenovirus
Atadenovirus
Genes
Viruses
Nucleic Acid Repetitive Sequences
Genetic Recombination

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Davison, A. J., Wright, K. M., & Harrach, B. (2000). DNA sequence of frog adenovirus. Journal of General Virology, 81(10), 2431-2439.

DNA sequence of frog adenovirus. / Davison, A. J.; Wright, K. M.; Harrach, B.

In: Journal of General Virology, Vol. 81, No. 10, 2000, p. 2431-2439.

Research output: Contribution to journalArticle

Davison, AJ, Wright, KM & Harrach, B 2000, 'DNA sequence of frog adenovirus', Journal of General Virology, vol. 81, no. 10, pp. 2431-2439.
Davison AJ, Wright KM, Harrach B. DNA sequence of frog adenovirus. Journal of General Virology. 2000;81(10):2431-2439.
Davison, A. J. ; Wright, K. M. ; Harrach, B. / DNA sequence of frog adenovirus. In: Journal of General Virology. 2000 ; Vol. 81, No. 10. pp. 2431-2439.
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