Diterpenoids from Euphorbia peplus

Judit Hohmann, Ferenc Evanics, László Berta, Tibor Bartók

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From a pro-inflammatory active extract of Euphorbia peplus, two new diterpene polyesters based on the pepluane and jatrophane skeletons were isolated, together with four known ingenane and jatrophane diterpenes. The structures were determined on the basis of extensive NMR studies. Ingenol 3- angelate, which was obtained for the first time from this plant, is an irritant toxin with high activity.

Original languageEnglish
Pages (from-to)291-294
Number of pages4
JournalPlanta Medica
Issue number3
Publication statusPublished - May 13 2000


ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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