Az endothelfunkció zavara szívbetegekben. Klasszifikáció, diagnosztikus és terápiás lehetöségek

Translated title of the contribution: Disturbance of endothelial function in heart disease patients. Classification, diagnostic and treatment options

B. Jusztina, H. István, K. Róbert Gábor, P. István

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Under physiologic circumstances the function of the cardiovascular system is based upon an intact endothelium. The different processes related to the endothelium sustain a steady-state between the constrictor and vasodilator, procoagulant and anticoagulant mediators, inflammatory and anti-inflammatory, growth-inhibiting and growth-stimulating substances. Endothelial dysfunction is considered to be a disturbance of this physiological steady state. It is the first step in the pathophysiology of atherosclerotic cardiovascular diseases, which precedes morphological changes and indicates disturbances of normal oxido-reduction processes of the cells. Beside description of some endothelium produced substances and presentation of their role in endothelial dysfunction, the clinical ascpects and examination of dysfunctious endothelium are shown. After description of the provocation tests (Ach, FMV) this paper presents patients with angina pectoris and normal coronarography where the confirmation of endothelial dysfunction is an important task.

Translated title of the contributionDisturbance of endothelial function in heart disease patients. Classification, diagnostic and treatment options
Original languageHungarian
Pages (from-to)210-220
Number of pages11
JournalOrvoskepzes
Volume76
Issue number3
Publication statusPublished - Jan 1 2001

ASJC Scopus subject areas

  • Medicine(all)

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