Distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches

E. Fehér, M. Fodor, G. Burnstock

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches of the cat was demonstrated by immunocytochemical techniques. A large number of immunoreactive nerve fibres was observed in the tela submucosa very close to the Peyer's patches. Some immunoreactive nerve cell bodies were also found in this layer. The immunoreactive nerve terminals ran around the margin of the follicles and only a few nerve fibres were observed in the centre of follicles. Electronmicroscopic investigation showed that these immunoreactive nerve terminals were in very close contact with lymphocytes and plasma cells, where no Schwann cell sheath was interposed. The gap between the nerve processes and the lymphocytes and plasma cells was about 20-200 nm, and occasionally less. These results provide morphological evidence consistent with the view that somatostatin has a neuroimmunomodulatory action.

Original languageEnglish
Pages (from-to)1195-1198
Number of pages4
JournalGut
Volume33
Issue number9
DOIs
Publication statusPublished - 1992

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Peyer's Patches
Somatostatin
Nerve Fibers
Plasma Cells
Neurilemma
Lymphocytes
Schwann Cells
Cats
Neurons

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Gastroenterology

Cite this

Distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches. / Fehér, E.; Fodor, M.; Burnstock, G.

In: Gut, Vol. 33, No. 9, 1992, p. 1195-1198.

Research output: Contribution to journalArticle

Fehér, E. ; Fodor, M. ; Burnstock, G. / Distribution of somatostatin-immunoreactive nerve fibres in Peyer's patches. In: Gut. 1992 ; Vol. 33, No. 9. pp. 1195-1198.
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