Distribution of proneuropeptide Y-derived peptides in the brain of Rana esculenta and Xenopus laevis

G. Lazar, J. L. Maderdrut, S. L. Trasti, Z. Liposits, P. Toth, T. Kozicz, I. Merchenthaler

Research output: Contribution to journalArticle

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Abstract

The distribution of proneuropeptide Y-containing perikarya and nerve fibers in the brain of Rana esculenta and Xenopus laevis was determined with antisera directed toward neuropeptide Y and the carboxyl terminal flanking peptide. The distribution of proneuropeptide Y-like immunoreactivity was similar in both anurans. In the telencephalon, immunoreactive perikarya were found in the olfactory bulb, all subdivisions of the pallium, the septum, pars lateralis of the amygdala, the nucleus accumbens, and the anterior preoptic area. In the diencephalon, labelled perikarya were detected in the ventromedial, ventrolateral and central thalamic nuclei, the magnocellular preoptic nucleus, the suprachiasmatic nucleus, the posterior tuberculum, and the infundibulum. Amacrine-like cells were stained in the retina. In the pretectal area, posterior thalamic neurons showed intense, Golgi-like immunostaining. In the mesencephalon, immunoreactive cells were found in the reticular nucleus, the anteroventral tegmental nucleus, the optic tectum, the interpeduncular nucleus, and the torus semicircularis. In the rhombencephalon, labelled perikarya were detected in the secondary visceral nucleus, the central gray, the nucleus of the solitary tract, the dorsal column nuclei, and the spinal nucleus of the trigeminal nerve. Immunoreactive nerve fibers were observed in all areas of the brain that contained labelled perikarya. The densest accumulations were found in the accessory olfactory bulb, pars lateralis of the amygdala, the ventral habenula, the posterior pituitary, the optic tectum, the interpeduncular nucleus, and the saccular nucleus. The distribution of proneuropeptide Y-like immunoreactivity in the anuran brain showed many similarities to the distribution described for the amniote brain.

Original languageEnglish
Pages (from-to)551-571
Number of pages21
JournalJournal of Comparative Neurology
Volume327
Issue number4
DOIs
Publication statusPublished - 1993

Fingerprint

Rana esculenta
Xenopus laevis
Peptides
Preoptic Area
Superior Colliculi
Olfactory Bulb
Brain
Amygdala
Nerve Fibers
Habenula
Ventral Thalamic Nuclei
Amacrine Cells
Diencephalon
Telencephalon
Rhombencephalon
Suprachiasmatic Nucleus
Trigeminal Nerve
Solitary Nucleus
Neuropeptide Y
Nucleus Accumbens

Keywords

  • amphibia
  • electron microscopy
  • evolution
  • hypothalamus
  • immunocytochemistry
  • neuroanatomy
  • neuropepti de Y
  • optic tectum
  • pancreatic polypeptide

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Distribution of proneuropeptide Y-derived peptides in the brain of Rana esculenta and Xenopus laevis. / Lazar, G.; Maderdrut, J. L.; Trasti, S. L.; Liposits, Z.; Toth, P.; Kozicz, T.; Merchenthaler, I.

In: Journal of Comparative Neurology, Vol. 327, No. 4, 1993, p. 551-571.

Research output: Contribution to journalArticle

Lazar, G. ; Maderdrut, J. L. ; Trasti, S. L. ; Liposits, Z. ; Toth, P. ; Kozicz, T. ; Merchenthaler, I. / Distribution of proneuropeptide Y-derived peptides in the brain of Rana esculenta and Xenopus laevis. In: Journal of Comparative Neurology. 1993 ; Vol. 327, No. 4. pp. 551-571.
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KW - optic tectum

KW - pancreatic polypeptide

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