Distribution of glial fibrillary acidic protein-immunopositive structures in the developing brain of the turtle Mauremys leprosa

M. Kálmán, G. Martin-Partido, M. Hidalgo-Sanchez, K. Majorossy

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

This study is a continuation of the description of the glial fibrillary acidic protein (GFAP)-immunopositive structures in the adult turtle brain and presents a comprehensive description of the development of these structures from the 20th embryonic day (E20) to the adult age. GFAP-immunopositive elements were first detected at E28 and by E34 the GFAP-immunopositivity was apparent throughout the brain, except the cerebellum. The appearance of GFAP seemed to be related to the end of cell migration and the formation of the thickened parts of the brain wall, such as the dorsal ventricular ridge. After hatching the pattern of the GFAP-immunopositivity differed from that in the adult only in minute details, except for the brain tracts in which GFAP-pattern was still changing due to myelination, and the molecular layer of the cerebellum in which a transverse fiber system appeared. The GFAP-positive elements belonged originally to the ependymoglia, but later the distortion due to the morphogenetic processes of branching and division changed the pattern almost beyond recognition. In some cases cell bodies - ependymal and non-ependymal - appeared to be GFAP-positive, but no astrocytes (i.e., stellate cells) were detected. The results are discussed in the light of previous observations on developing mammalian, avian and lizard brains.

Original languageEnglish
Pages (from-to)47-65
Number of pages19
JournalAnatomy and Embryology
Volume196
Issue number1
DOIs
Publication statusPublished - 1997

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Turtles
Glial Fibrillary Acidic Protein
Brain
Cerebellum
Lizards
Astrocytes
Cell Movement
Embryonic Structures

Keywords

  • Development of glia
  • Development of turtle brain
  • GFAP
  • Turtle glia

ASJC Scopus subject areas

  • Anatomy
  • Developmental Biology
  • Cell Biology
  • Embryology

Cite this

Distribution of glial fibrillary acidic protein-immunopositive structures in the developing brain of the turtle Mauremys leprosa. / Kálmán, M.; Martin-Partido, G.; Hidalgo-Sanchez, M.; Majorossy, K.

In: Anatomy and Embryology, Vol. 196, No. 1, 1997, p. 47-65.

Research output: Contribution to journalArticle

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