Distribution of galanin-like immunoreactivity in the brain of Rana esculenta and Xenopus laevis

G. Y. Lazar, Z. Liposits, P. Toth, S. L. Trasti, J. L. Maderdrut, I. Merchenthaler

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

The immunocytochemical distribution of galanin-containing perikarya and nerve terminals in the brain of Rana esculenta and Xenopus laevis was determined with antisera directed toward either porcine or rat galanin. The pattern of galanin-like immunoreactivity appeared to be identical with antisera directed toward either target antigen. The distribution of galanin-like immunoreactivity was similar in Rana esculenta and Xenopus laevis except for the absence of a distinct laminar distribution of immunoreactivity in the optic tectum of Xenopus laevis. Galanin-containing perikarya were located in all major subdivisions of the brain except the metencephalon. In the telencephalon, immunoreactive perikarya were detected in the pars medialis of the amygdala and the preoptic area. In the diencephalon, immunoreactive perikarya were detected in the caudal half of the suprachiasmatic nucleus, the nucleus of the periventricular organ, the ventral hypothalamus, and the median eminence. In the mesencephalon, immunoreactive perikarya were detected near the midline of the rostroventral tegmentum, in the torus semicircularis and, occasionally, in lamina A and layer 6 of the optic tectum. In the myelencephalon, labelled perikarya were detected only in the caudal half of the nucleus of the solitary tract. Immunoreactive nerve fibers of varying density were observed in all subdivisions of the brain with the densest accumulations of fibers occurring in the pars lateralis of the amygdala and the preoptic area. Dense accumulations of nerve fibers were also found in the lateral septum, the medial forebrain bundle, the periventricular region of the diencephalon, the ventral hypothalamus, the median eminence, the mesencephalic central gray, the laminar nucleus of the torus semicircularis, several laminae of the optic tectum, the interpeduncular nucleus, the isthmic nucleus, the central gray of the rhombencephalon, and the dorsolateral caudal medulla. The extensive system of galanin-containing perikarya and nerve fibers in the brain of representatives of two families of anurans showed many similarities to the distribution of galanin-containing perikarya and nerve fibers previously described for the mammalian brain.

Original languageEnglish
Pages (from-to)45-67
Number of pages23
JournalJournal of Comparative Neurology
Volume310
Issue number1
DOIs
Publication statusPublished - 1991

Fingerprint

Rana esculenta
Galanin
Xenopus laevis
Nerve Fibers
Brain
Superior Colliculi
Diencephalon
Median Eminence
Preoptic Area
Amygdala
Hypothalamus
Myelencephalon
Immune Sera
Metencephalon
Medial Forebrain Bundle
Telencephalon
Periaqueductal Gray
Rhombencephalon
Suprachiasmatic Nucleus
Solitary Nucleus

Keywords

  • evolution
  • frog
  • immunocytochemistry
  • neuroanatomy
  • neuroendocrinology neuropeptides
  • optic tectum
  • vision

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Distribution of galanin-like immunoreactivity in the brain of Rana esculenta and Xenopus laevis. / Lazar, G. Y.; Liposits, Z.; Toth, P.; Trasti, S. L.; Maderdrut, J. L.; Merchenthaler, I.

In: Journal of Comparative Neurology, Vol. 310, No. 1, 1991, p. 45-67.

Research output: Contribution to journalArticle

Lazar, G. Y. ; Liposits, Z. ; Toth, P. ; Trasti, S. L. ; Maderdrut, J. L. ; Merchenthaler, I. / Distribution of galanin-like immunoreactivity in the brain of Rana esculenta and Xenopus laevis. In: Journal of Comparative Neurology. 1991 ; Vol. 310, No. 1. pp. 45-67.
@article{44711778f7024df4a1e67855d6bb3d2d,
title = "Distribution of galanin-like immunoreactivity in the brain of Rana esculenta and Xenopus laevis",
abstract = "The immunocytochemical distribution of galanin-containing perikarya and nerve terminals in the brain of Rana esculenta and Xenopus laevis was determined with antisera directed toward either porcine or rat galanin. The pattern of galanin-like immunoreactivity appeared to be identical with antisera directed toward either target antigen. The distribution of galanin-like immunoreactivity was similar in Rana esculenta and Xenopus laevis except for the absence of a distinct laminar distribution of immunoreactivity in the optic tectum of Xenopus laevis. Galanin-containing perikarya were located in all major subdivisions of the brain except the metencephalon. In the telencephalon, immunoreactive perikarya were detected in the pars medialis of the amygdala and the preoptic area. In the diencephalon, immunoreactive perikarya were detected in the caudal half of the suprachiasmatic nucleus, the nucleus of the periventricular organ, the ventral hypothalamus, and the median eminence. In the mesencephalon, immunoreactive perikarya were detected near the midline of the rostroventral tegmentum, in the torus semicircularis and, occasionally, in lamina A and layer 6 of the optic tectum. In the myelencephalon, labelled perikarya were detected only in the caudal half of the nucleus of the solitary tract. Immunoreactive nerve fibers of varying density were observed in all subdivisions of the brain with the densest accumulations of fibers occurring in the pars lateralis of the amygdala and the preoptic area. Dense accumulations of nerve fibers were also found in the lateral septum, the medial forebrain bundle, the periventricular region of the diencephalon, the ventral hypothalamus, the median eminence, the mesencephalic central gray, the laminar nucleus of the torus semicircularis, several laminae of the optic tectum, the interpeduncular nucleus, the isthmic nucleus, the central gray of the rhombencephalon, and the dorsolateral caudal medulla. The extensive system of galanin-containing perikarya and nerve fibers in the brain of representatives of two families of anurans showed many similarities to the distribution of galanin-containing perikarya and nerve fibers previously described for the mammalian brain.",
keywords = "evolution, frog, immunocytochemistry, neuroanatomy, neuroendocrinology neuropeptides, optic tectum, vision",
author = "Lazar, {G. Y.} and Z. Liposits and P. Toth and Trasti, {S. L.} and Maderdrut, {J. L.} and I. Merchenthaler",
year = "1991",
doi = "10.1002/cne.903100106",
language = "English",
volume = "310",
pages = "45--67",
journal = "Journal of Comparative Neurology",
issn = "0021-9967",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Distribution of galanin-like immunoreactivity in the brain of Rana esculenta and Xenopus laevis

AU - Lazar, G. Y.

AU - Liposits, Z.

AU - Toth, P.

AU - Trasti, S. L.

AU - Maderdrut, J. L.

AU - Merchenthaler, I.

PY - 1991

Y1 - 1991

N2 - The immunocytochemical distribution of galanin-containing perikarya and nerve terminals in the brain of Rana esculenta and Xenopus laevis was determined with antisera directed toward either porcine or rat galanin. The pattern of galanin-like immunoreactivity appeared to be identical with antisera directed toward either target antigen. The distribution of galanin-like immunoreactivity was similar in Rana esculenta and Xenopus laevis except for the absence of a distinct laminar distribution of immunoreactivity in the optic tectum of Xenopus laevis. Galanin-containing perikarya were located in all major subdivisions of the brain except the metencephalon. In the telencephalon, immunoreactive perikarya were detected in the pars medialis of the amygdala and the preoptic area. In the diencephalon, immunoreactive perikarya were detected in the caudal half of the suprachiasmatic nucleus, the nucleus of the periventricular organ, the ventral hypothalamus, and the median eminence. In the mesencephalon, immunoreactive perikarya were detected near the midline of the rostroventral tegmentum, in the torus semicircularis and, occasionally, in lamina A and layer 6 of the optic tectum. In the myelencephalon, labelled perikarya were detected only in the caudal half of the nucleus of the solitary tract. Immunoreactive nerve fibers of varying density were observed in all subdivisions of the brain with the densest accumulations of fibers occurring in the pars lateralis of the amygdala and the preoptic area. Dense accumulations of nerve fibers were also found in the lateral septum, the medial forebrain bundle, the periventricular region of the diencephalon, the ventral hypothalamus, the median eminence, the mesencephalic central gray, the laminar nucleus of the torus semicircularis, several laminae of the optic tectum, the interpeduncular nucleus, the isthmic nucleus, the central gray of the rhombencephalon, and the dorsolateral caudal medulla. The extensive system of galanin-containing perikarya and nerve fibers in the brain of representatives of two families of anurans showed many similarities to the distribution of galanin-containing perikarya and nerve fibers previously described for the mammalian brain.

AB - The immunocytochemical distribution of galanin-containing perikarya and nerve terminals in the brain of Rana esculenta and Xenopus laevis was determined with antisera directed toward either porcine or rat galanin. The pattern of galanin-like immunoreactivity appeared to be identical with antisera directed toward either target antigen. The distribution of galanin-like immunoreactivity was similar in Rana esculenta and Xenopus laevis except for the absence of a distinct laminar distribution of immunoreactivity in the optic tectum of Xenopus laevis. Galanin-containing perikarya were located in all major subdivisions of the brain except the metencephalon. In the telencephalon, immunoreactive perikarya were detected in the pars medialis of the amygdala and the preoptic area. In the diencephalon, immunoreactive perikarya were detected in the caudal half of the suprachiasmatic nucleus, the nucleus of the periventricular organ, the ventral hypothalamus, and the median eminence. In the mesencephalon, immunoreactive perikarya were detected near the midline of the rostroventral tegmentum, in the torus semicircularis and, occasionally, in lamina A and layer 6 of the optic tectum. In the myelencephalon, labelled perikarya were detected only in the caudal half of the nucleus of the solitary tract. Immunoreactive nerve fibers of varying density were observed in all subdivisions of the brain with the densest accumulations of fibers occurring in the pars lateralis of the amygdala and the preoptic area. Dense accumulations of nerve fibers were also found in the lateral septum, the medial forebrain bundle, the periventricular region of the diencephalon, the ventral hypothalamus, the median eminence, the mesencephalic central gray, the laminar nucleus of the torus semicircularis, several laminae of the optic tectum, the interpeduncular nucleus, the isthmic nucleus, the central gray of the rhombencephalon, and the dorsolateral caudal medulla. The extensive system of galanin-containing perikarya and nerve fibers in the brain of representatives of two families of anurans showed many similarities to the distribution of galanin-containing perikarya and nerve fibers previously described for the mammalian brain.

KW - evolution

KW - frog

KW - immunocytochemistry

KW - neuroanatomy

KW - neuroendocrinology neuropeptides

KW - optic tectum

KW - vision

UR - http://www.scopus.com/inward/record.url?scp=0025954014&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025954014&partnerID=8YFLogxK

U2 - 10.1002/cne.903100106

DO - 10.1002/cne.903100106

M3 - Article

VL - 310

SP - 45

EP - 67

JO - Journal of Comparative Neurology

JF - Journal of Comparative Neurology

SN - 0021-9967

IS - 1

ER -