Distribution of FMRFamide-like immunoreactive neurons in the central nervous system of the snail Helix pomatia

K. Elekes, D. R. Nässel

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Abstract

The distribution of FMRFamide-like immunoreactive (FLI) neurons and their morphological characteristics have been investigated in the central nervous system of the snail, Helix pomatia L. Approximately phageal ganglion complex. More than 50% of the FLI neurons were located in the cerebral ganglia. The FLI neurons could be divided into four groups according to size: (i) giant neurons (over 100 μm); (ii) large neurons (80-100 μm); (iii) medium-sized neurons (40-70 μm); (iv) small neurons (12-30 μm). They were distributed i) in groups or clusters, typical of small neurons and ii) in solitary form or in groups comprising 2-3 cells, typical of large and giant neurons. Giant and large neurons revealed only limited arborizations in the neuropil, but rich branching towards and in the peripheral nerves. Some of the small neurons had extensive arborizations of varicose fibers in the neuropil. They may therefore play some role in integratory processes. Varicose FLI fibers were visualized in the cell body layer of the different ganglia, and in the neural sheath of both the ganglia and the peripheral nerves. We propose a multifunctional involvement of FLI neurons and FMRFamide-like neuropeptides in the Helix nervous system: (i) a synaptic or modulatory role in axo-axonic interactions in the neuropil; (ii) a direct influence on neuronal cell bodies in the cortical layer, (iii) innervation of different peripheral organs; and (iv) remote neurohormonal control of peripheral events through the neural sheath.

Original languageEnglish
Pages (from-to)177-190
Number of pages14
JournalCell and Tissue Research
Volume262
Issue number1
DOIs
Publication statusPublished - Oct 1990

Fingerprint

Helix (Snails)
FMRFamide
Neurology
Neurons
Central Nervous System
Ganglia
Neuropil
Peripheral Nerves
Cells
Fibers
Remote control
Neuropeptides
Nervous System

Keywords

  • FMRFamide
  • Helix pomatia (Mollusca)
  • Immunocytochemistry
  • Nervous system, central
  • Neurohormones
  • Neuropeptide

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology

Cite this

Distribution of FMRFamide-like immunoreactive neurons in the central nervous system of the snail Helix pomatia. / Elekes, K.; Nässel, D. R.

In: Cell and Tissue Research, Vol. 262, No. 1, 10.1990, p. 177-190.

Research output: Contribution to journalArticle

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