Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues

I. Pizarro, M. M. Gómez, P. Fodor, M. A. Palacios, C. Cámara

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

This study evaluated the bioaccumulation and biotransformation of arsenic species in chicken heart and meat tissues. The experimental study was carried out using two sets of samples. In the first one, 10-d-old chickens were exposed to sodium arsenate, using spiked drinking water. These chickens grew normally and were killed after 50 d of arsenic exposure. The second set were edible chickens used as blanks for a parallel study. The total arsenic and arsenic species content in the exposed samples were at least twice those in the normal edible chicken. It has been demonstrated that sodium arsenate is biotransformed to arsenite and an unknown species and its distribution varies among the different cardiac and meat tissues. One important aspect is the capability of the auricle to preconcentrate the most toxic species, arsenite, in the exposed chicken. A nonidentified arsenic species from the edible chicken was detected. Arsenobetaine was also detected in several tissues. This article shows that chicken can be used as a representative animal when considering inorganic arsenic exposure in humans.

Original languageEnglish
Pages (from-to)129-143
Number of pages15
JournalBiological Trace Element Research
Volume99
Issue number1-3
DOIs
Publication statusPublished - Jun 2004

Fingerprint

Arsenic
Biotransformation
Muscle
Chickens
Myocardium
Tissue
Muscles
Meats
Meat
Bioaccumulation
Poisons
Drinking Water
Animals

Keywords

  • As species
  • Biotransformation
  • Cardiovascular tissues
  • Chicken
  • HPLC-ICP-MS

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues. / Pizarro, I.; Gómez, M. M.; Fodor, P.; Palacios, M. A.; Cámara, C.

In: Biological Trace Element Research, Vol. 99, No. 1-3, 06.2004, p. 129-143.

Research output: Contribution to journalArticle

Pizarro, I. ; Gómez, M. M. ; Fodor, P. ; Palacios, M. A. ; Cámara, C. / Distribution and biotransformation of arsenic species in chicken cardiac and muscle tissues. In: Biological Trace Element Research. 2004 ; Vol. 99, No. 1-3. pp. 129-143.
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